Human Lung Fibroblast Cell Line

The human lung fibroblast cell line mrc 5 constitutively produces a megakaryocyte potentiator activity identified in murine bone marrow liquid culture assays for acetylcholinesterase and megakaryocyte colony assays in the presence of low concentrations of il 3.

Human lung fibroblast cell line.

Jacobs the cell line was derived from the human lung tissue of a 14 week old male fetus aborted from a 27 year old woman. Wi 38 is a diploid human cell line composed of fibroblasts derived from lung tissue of a 3 month gestation aborted female fetus. Fibroblast tissue. The mrc 5 cell line was derived from normal lung tissue of a 14 week old male fetus by j p.

Human cell type. Our normal human fibroblasts can also be used for drug screening. Cc 2512b and get a discounted price on cells and media. The modal chromosome number was 46 occurring in 70 of cells.

Make sure that the caps of all components are tight thaw the components of fibroblast growth kit low serum atcc pcs 201 041 just prior to adding them to the fibroblast basal medium atcc pcs 201 030. This is a normal diploid human cell line with 46 xy karyotype. Initiated in september 1966 by j. The kit consists of a cryopreserved ampule of lung fibroblast cells catalog no.

Cc 2512 and fgm tm 2 bulletkit tm growth media catalog no. Fluorescence digital image gallery human fetal lung fibroblast cells mrc 5 line the mrc 5 cell line is commonly utilized in vaccine development as a transfection host in virology research and for in vitro cytotoxicity testing. Human fetal lung fibroblasts such as hfll mrc 5 and wi38 have been extensively studied and characterized in aging studies collagen biosynthesis and cytotoxicity testing. Lung disease.

The cell line isolated by leonard hayflick in the 1960s has been used extensively in scientific research with applications ranging from developing important theories in molecular biology and aging to the production of most human virus vaccines. 2 continuous lung cell lines. Bladder cardiac dermal gingival lung airway prostate scleral uterine and vas deferens. Purchase our lung fibroblast cell culture kit catalog no.

A certificate of analysis is provided for each cell lot purchased. The production levels of this activity were increased after stimulation with the. Normal human atcc pcs 201 013 from the liquid nitrogen tank. 26 29 the fibroblasts are easily maintained in culture and exhibit a finite life span.

Jacobs in september of 1966. The cells are derived from a first trimester fetus. A brief history of imr 90. Lifeline normal human fibroblasts provide an ideal cell system to study wound healing toxicology cancer or basic cell biology in various organs including skin lung bladder and the reproductive systems.