Hiv Treated With Stem Cells

The man had hodgkin lymphoma a cancer of the lymphatic system a key part of our immune system. In this case however there was a second goal. Wednesday july 2 healthday news two hiv positive patients show no trace of virus after receiving chemotherapy and stem cell transplants as treatment for lymphoma according to new research.

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The stem cells came from a donor who carried a rare.

Hiv treated with stem cells.

Uk patient free of hiv after stem cell treatment reports bbc news. He had chemotherapy to treat the hodgkin s cancer and in addition stem cells were implanted into the patient from a donor resistant to hiv leading to both his cancer and hiv going into remission. The twist was tim s bone marrow donor was immune to hiv. As the donor has a very rare genetic mutation ccr5 delta 32 that makes them hiv resistant the stem cells sent the hiv into remission with only a mild reaction from the treatment.

Tim received two transplants of bone marrow stem cells one from this hiv immune donor. Doctors report that a man with hiv who was given a stem cell transplant to treat his blood cancer has no detectable signs of hiv 18 months after stopping anti hiv treatment. Hiv treatment has been stymied because reservoirs of infected cells have remained latent or in hiding in the bone marrow of patients and can later reactivate. This is one of the standard bone cancer treatments.

Brown s leukemia but. Stem cell transplants are an established treatment for the cancer. He received a stem cell transplant from a donor. Receiving stem cells from this donor it turned out not only treated mr.

He looked for a donor with a specific genetic mutation that made them practically immune to hiv. Treatment with anti virals. To cure the patient s hiv. But in order to treat the lymphoma with stem cells doctors needed to find a donor who was resistant to his other condition hiv the virus that causes aids.

To treat his leukemia his doctors wanted to wipe out his immune system with radiation and chemotherapy and then rebuild it with donated stem cells. After the stem cell treatment which involved replacing the patient s white blood cells with hiv resistant versions the patient was deemed as in remission.